The Itch Journey - Quiz

< back to article listing page

The Itch Journey - Quiz

Tags:
The Itch Journey
Aug 07 2024

 

 

The Itch Journey - Quiz

1. True or False

a. Itch significantly affects sleep and quality of life in AD and PN patients
Select the correct answer
b. Itch is more severe in patients with PN compared to other inflammatory diseases
Select the correct answer
c. Itch can affect personal and social life of patients with AD or PN
Select the correct answer
d. Patients with AD rank sleep disturbance among their top 3 most problematic symptoms
Select the correct answer
e. In AD and PN, the cascade of events that trigger itch involves both immune and nervous systems
Select the correct answer
2. Which of the following social aspects of a patient’s life are impacted by AD or PN disease?
Select the correct answer
3. Which of the statements below is false?
Select the correct answer
4. What are the 3 hallmarks of AD?
Select the correct answer
5. What are the 4 hallmarks of PN?
Select the correct answer
6. Which cytokine has not been implicated in AD or PN pathophysiology?
Select the correct answer
7. Which of the following scales is not used to measure itch in patients with AD or PN?
Select the correct answer

References:

  1. Bashyam A, et al. Lifelong impact of severe atopic dermatitis on quality of life: a case report. Dermatol Ther (Heidelb). 2021;11:1065-1070
  2. Cevikbas F, Lerner EA. Physiology and pathophysiology of itch. Physiol Rev. 2020;100(3):945-982. doi:10.1152/physrev.00017.2019
  3. McCleary KK. More than skin deep. 2020. http://www.morethanskindeep-eczema.org/uploads/1/2/5/3/125377765/mtsd_report_-_digital_file.pdf
  4. Steinke S, et al. Humanistic burden of chronic pruritus in patients with inflammatory dermatoses: Results of the European Academy of Dermatology and Venereology Network on Assessment of Severity and Burden of Pruritus (PruNet) cross-sectional trial. J Am Acad Dermatol. 2018;79(3):457–463.e5. 
  5. Rodriguez D, et al. Patient perspectives on living with severe prurigo nodularis. JAMA Dermatol. 2023;159(11):1205–1212. doi:10.1001/jamadermatol.2023.3251
  6. Pereira MP, et al. Prurigo nodularis: a physician survey to evaluate current perceptions of its classification, clinical experience and unmet need. J Eur Acad Dermatol Venereol. 2018;32(12):2224-2229. doi:10.1111/jdv.15107
  7. Ständer S. Atopic dermatitis. N Engl J Med. 2021;384(12):1136–1143. 
  8. Belzberg M, et al. Prurigo nodularis is characterized by systemic and cutaneous T helper 22 immune polarization. J Invest Dermatol. 2021;141(9):2208–2218.e14. doi:10.1016/j.jid.2021.02.749
  9. Ständer S, et al. IFSI-guideline on chronic prurigo including prurigo nodularis. Itch. 2020;5:e42
  10. Sutaria N, et al. Cutaneous transcriptomics identifies fibroproliferative and neurovascular gene dysregulation in prurigo nodularis compared with psoriasis and atopic dermatitis. J Invest Dermatol. 2022;142(9):2537-2540. doi:10.1016/j.jid.2022.02.010
  11. Zeidler C, et al. Chronic prurigo of nodular type: a review. Acta Derm Venerol. 2018;98(2):173–179
  12. Borgia F, et al. IL-31: state of the art for an inflammation-oriented interleukin. Int J Mol Sci. 2022, 10;23(12):6507. doi: 10.3390/ijms23126507
  13. Dillon SR, Sprecher C, Hammond A, et al. Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice. Nat Immunol. 2004;5(7):752-760
  14. Williams KA, et al. Prurigo nodularis: pathogenesis and management. J Am Acad Dermatol. 2020;83(6):1567-1575
  15. Dubin, C, Del Duca E, Guttman-Yassky E. The IL-4, IL-13 and IL-31 pathways in atopic dermatitis. Expert Rev Clin Immunol. 2021;17(8):835-852. doi:10.1080/1744666X.2021.1940962
  16. Ingrasci G, Lipman ZM, Hawash AA, et al. The pruritogenic role of the type 2 immune response in diseases associated with chronic itch. Exp Dermatol. 2021;30(9):1208-1217
  17. Eichenfield, L. F., et al. Guidelines of care for the management of atopic dermatitis: section 1. Diagnosis and assessment of atopic dermatitis. Journal of the American Academy of Dermatology,. 2014; 70(2), 338–351. https://doi.org/10.1016/j.jaad.2013.10.010
  18. Pereira MP, Ständer S. Measurement tools for chronic pruritus: assessment of the symptom and the associated burden: a review. Itch. 2019;4(4):e29. doi:10.1097/itx.0000000000000029  

Interested in learning more?

Sign up for more information about itch, atopic dermatitis, and prurigo nodularis by submitting the form below.

Required.